Applications
In order to obtain reliable
results in clinical and diagnostic PCR work, it is necessary to maintain
an ultra-clean work environment that is free from biological and particulate
contamination.
Additionally, UV radiation
is needed to destroy post-procedure contaminants. Clyde-Apac
PCR60™ cabinets provide a high degree of protection for products and apparatus
in PCR applications.
The PCR60R™ is a variant
of the basic PCR cabinet, and provides protection for both personnel and
products.
Description
PCR60 cabinets
Cabinets are vertical laminar
flow workstations designed for installation on standard laboratory benches,
or on optional floor stands. Their compact dimensions reduce the need for
bench space.
They are designed and manufactured
in Australia, and each unit is factory-tested and certified by a NATA-registered
laboratory.
Please refer to our Standards
page.
Vertical laminar airflow
in the work zone creates a biologically-clean, particle-free work environment
that reduces cross contamination during sample preparation. Partial recirculation
of air leaving the work zone reduces air turbulence and extends HEPA filter
life.
A short-wavelength UV lamp
inactivates residual DNA/RNA particles, thus reducing
carryover contamination. The UV operates only with the fan switched off,
and the UV shield should be fitted whenever the UV lamp is in use.
PCR60R Cabinets
In addition to the product
protection afforded by PCR60 cabinets, the PCR60R provides protection for
personnel. This is achieved by an air barrier at the work opening and HEPA
filtration of the exhaust air.
An air barrier between the
operator and the work zone is maintained by a flow of room air into a grille
in the work opening. All positive pressure zones are surrounded by negative
pressure zones, so as to contain hazardous aerosols.
Easy-to-clean stainless-steel
work area
Construction
Cabinet.
The sturdy steel housing
is finished in a durable baked enamel that has been developed for laboratory
equipment. The work zone and the removable UV shield are constructed in
easy-to-clean 304 stainless-steel.
Fan.
A direct-drive fan is regulated
by a speed controller to enable airflow to be maintained through filter
life. The fan and filter plenums are designed to provide ultra-quiet, low-vibration
operation.
HEPA filter.
Clyde-Apac Microseal™ HEPA
filters are manufactured to the most exacting standards for critical applications.
Each filter is individually certified to achieve efficiency of not less
than 99.995% to the stringent BS3928 Sodium Flame test. All testing is
conducted in a NATA-registered factory laboratory and a NATA-endorsed test
label, being an extract of the test report, is affixed to each filter.
Prefilter.
On PCR60 cabinets, an easily-accessed,
washable prefilter on top of the unit arrests not less than 90% of particles
5 micron and larger, thus prolonging HEPA filter life.

Physical Data
Model
|
Overall dimensions
(mm)
|
Work zone dimensions
(mm)
|
Weight
(kg)
|
|
W
|
D
|
H
|
W
|
D
|
H
|
|
PCR60
|
676
|
690
|
1000
|
576
|
575
|
525
|
70
|
PCR60R
|
676
|
690
|
1055
|
576
|
575
|
525
|
86
|
Personnel Protection -
Limitations
PCR60 cabinets provide protection
for products or experiments, but do not protect personnel from aerosols
of hazardous materials that may be handled in the cabinet. For PCR applications
where protection for products and personnel is required, PCR60R safety
cabinets should be considered.
Options
Manometer
Power outlet
Service taps for air, gas and
vacuum
Floor stand
Trolley
Fumigation adapters (PRC6OR)
Hourmeter
Quality Assurance
and Control
Clyde-Apac laminar flow
and HEPA filter products are manufactured in Australia under an accredited
Quality Management system.
Please refer to our Standards
page.
On-Site Testing
PCR Series cabinets are
factory-tested and certified by a NATA-registered laboratory. Additional
testing and certification is recommended as follows:
On site prior to use
After any electrical or mechanical
maintenance
After filter replacement
After re-location
At least annually
In special circumstances, e.g.
if faulty cabinet operation is suspected
AES Environmental is a
NATA-registered laboratory and provides comprehensive on-site maintenance,
testing and certification services for safety cabinets, laminar flow
work stations, cleanrooms and HEPA filter
installations. This service is available from fully- equipped laboratories
in major Australian centres.
Due to ongoing research
& development, Clyde-Apac reserves the right to modify the product
& specifications without notice.
|